FABRICATION, APPRAISAL, AND TRANSDERMAL PERMEATION OF SILDENAFIL CITRATE-LOADED NANOSTRUCTURED LIPID CARRIERS VERSUS SOLID LIPID NANOPARTICLES

Fabrication, appraisal, and transdermal permeation of sildenafil citrate-loaded nanostructured lipid carriers versus solid lipid nanoparticles

Yosra SR Elnaggar1, Magda A El-Massik2, Ossama Y Abdallah11Department of Pharmaceutics, Faculty of Pharmacy, Alexandria University, 2Department of Pharmaceutics, Faculty of Pharmacy and Drug Manufacturing, Pharos University, Alexandria, EgyptAbstract: Although sildenafil citrate (SC) is used extensively for erectile dysfunction, oral delivery of SC

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Relationship between plasma xanthine oxidoreductase activity and left ventricular ejection fraction and hypertrophy among cardiac patients.

Background and purposeXanthine oxidoreductase (XOR), which catalyzes purine catabolism, has two interconvertible forms, xanthine dehydrogenase and xanthine oxidase, the latter of which produces superoxide during uric acid (UA) synthesis.An association between plasma XOR activity and cardiovascular and renal outcomes has been previously suggested.We

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